Broadcast overview

An AI-generated overview based on this broadcast's transcript.

UK government services and multiple sites around the world, including parts of Amazon and Wikipedia, were offline as experts worked to fix a major cyber security issue that led to millions of hacking attempts; AI systems brought the problem to light. Barclays is to cut around 5,000 jobs this year as it turns to artificial intelligence to streamline operations and reduce costs, but has not revealed how many UK roles will be axed. Further arrests were made after a police officer was shot in the foot in Nottingham city centre on Sunday: a 35-year-old man and a 33-year-old woman were arrested in the Nottingham area yesterday, and a 21-year-old was arrested in London on Tuesday; the officer remains in a stable condition.

A new clinical trial backed by the Prime Minister could dramatically speed up the discovery of treatments for Alzheimer's disease, with medicines initially for ADHD and diabetes that may help reduce brain inflammation studied to see if they can be repurposed. Dame Judi Dench said she is no longer able to work because of her eye condition; the 91-year-old was diagnosed with age-related macular degeneration in 2012, which has made it difficult to recognise people's faces, and she said she cannot read anymore and is unable to do films or be on stage.

Four contenders have reached the shortlist for City of Culture 2029: Blackpool, Milton Keynes, Sheffield and Wrexham. Each will receive at least £125,000 to progress its bid, and the winner will get funding worth £10 million. A weather forecast warned of an amber wind warning going live at 1 a.m., with severe gales developing over the southwest and a broader yellow wind warning covering central and western England and Wales tonight and into tomorrow; Storm Austin was expected to continue into Friday with high waves, flying debris and a risk of flooding, while a rain warning for Scotland indicated heavy and persistent rain.

  1. 0:00
  2. 0:03

    Claim UK takes 32 government services offline in global PHP cyber alert

    Cloudflare's CEO said attempted exploitation rose from thousands in the 10 hours before the public announcement to tens of thousands within 45 minutes, hundreds of thousands within two hours, and millions by the time of his post.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:03-0:12

  3. 0:08

    Claim UK takes 32 government services offline in global PHP cyber alert

    The PHP vulnerability was reportedly discovered using AI by Wiz and independently by OpenAI.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:08-0:18

  4. 0:12

    Claim Barclays to cut around 5,000 jobs by end of year in AI push

    Barclays planned or was expected to cut around 5,000 jobs this year, with the reductions expected by the end of the year.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:12-0:25

  5. 0:12

    Claim Barclays to cut around 5,000 jobs by end of year in AI push

    Barclays was turning to AI to streamline operations, reduce costs and improve efficiency, with AI central to the job cuts.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:12-0:25

  6. 0:14
  7. 0:30
  8. 0:30

    Claim Aisha Zaman charged over Nottingham police officer shooting

    Two men and two women were arrested after the shooting.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:30-0:43

  9. 0:39

    Claim Aisha Zaman charged over Nottingham police officer shooting

    The wounded officer was in a stable condition in hospital.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:39-0:47

  10. 0:43
  11. 0:51

    Claim Prime Minister-backed Alzheimer's trial tests repurposed diabetes and ADHD drugs

    The trial will initially test medicines for ADHD and diabetes to see whether they can be repurposed.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:51-1:00

  12. 0:55

    Claim Judi Dench says macular degeneration means she can no longer act

    Dame Judi Dench said an eye condition has left her unable to work, read, or appear in films or on stage.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:55-1:07

  13. 0:55

    Claim Judi Dench says macular degeneration means she can no longer act

    Dame Judi Dench said an eye condition has left her unable to work, read, or appear in films or on stage.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 0:55-1:07

  14. 1:00
  15. 1:04

    Claim Judi Dench says macular degeneration means she can no longer act

    Dame Judi Dench said an eye condition has left her unable to work, read, or appear in films or on stage.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 1:04-1:11

  16. 1:11

    Claim Judi Dench says macular degeneration means she can no longer act

    Dame Judi Dench said an eye condition has left her unable to work, read, or appear in films or on stage.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 1:11-1:21

  17. 1:11

    Claim Judi Dench says macular degeneration means she can no longer act

    Dame Judi Dench said an eye condition has left her unable to work, read, or appear in films or on stage.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 1:11-1:21

  18. 1:15
  19. 1:21

    Claim Blackpool, Milton Keynes, Sheffield and Wrexham shortlisted for UK City of Culture 2029

    Blackpool, Milton Keynes, Sheffield and Wrexham were shortlisted for UK City of Culture 2029.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 1:21-1:30

  20. 1:21

    Claim Blackpool, Milton Keynes, Sheffield and Wrexham shortlisted for UK City of Culture 2029

    Blackpool, Milton Keynes, Sheffield and Wrexham were shortlisted for UK City of Culture 2029.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 1:21-1:30

  21. 1:25

    Claim Blackpool, Milton Keynes, Sheffield and Wrexham shortlisted for UK City of Culture 2029

    Each shortlisted place was to receive £125,000 toward its final bid.

    Channel 5, 5 News at Lunchtime, 22 October 2026, 1:25-1:35

  22. 1:39
    ~3 min without annotations

Source: 5, "5 News at Lunchtime", Thursday 22 October 2026. Transcript excerpts and stills are shown only to support the analysis annotated alongside them. Search-result excerpts are distinct from the editorial annotations — see our copyright basis. The full broadcast is not reproduced.